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Protein Ontology report - smad2 isoform Long phosphorylated 1 (human)
PR:000025934 -
http://purl.obolibrary.org/obo/PR_000025934
Complex
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000025934
PRO name
smad2 isoform Long phosphorylated 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hSMAD2/iso:Long/Phos:1
PRO-proteoform-std
:
EXACT:
UniProtKB:Q15796-1
, Ser-465/Ser-467,
MOD:00046
Definition
"A smad2 isoform Long phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif.
UniProtKB:Q15796-1
, Ser-465/Ser-467,
MOD:00046
." [
PMID:8980228
,
PMID:9346966
]
Comment
Kinase=("TGFBR1";
PR:000025963
; Ser-465/Ser-467).
PRO Category
organism-modification
Parent
PR:000000650
smad2 isoform Long phosphorylated 1
PR:Q15796
mothers against decapentaplegic homolog 2 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
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hSMAD2/iso:Long/Phos:1
forms found in complexes
hSMAD2/iso:Long/Phos:1
Component
Complexes
PR:000025934
hSMAD2/iso:Long/Phos:1
PR:000025933
smad2-smad4 protein complex 1 (human)
PR:000025951
smad2-smad4-ski protein complex 1 (human)
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000025934
hSMAD2/iso:Long/Phos:1
UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046
acts_upstream_of_or_within
GO:0006355
regulation of DNA-templated transcription
PMID:15690394
;
PMID:9689110
GO:0007165
signal transduction
PMID:8752209
;
PMID:8980228
;
PMID:9346966
GO:0007179
transforming growth factor beta receptor signaling pathway
PMID:8752209
;
PMID:8980228
GO:0060395
SMAD protein signal transduction
PMID:9346966
enables
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
PMID:8980228
;
PMID:9346966
GO:0003713
transcription coactivator activity
PMID:9689110
GO:0046332
SMAD binding
PMID:9311995
located_in
GO:0005634
nucleus
PMID:9006934
;
PMID:9346966